SMARCA4 / BRG1 Monoclonal Antibody (3G4), Active Motif™

Rat Monoclonal Antibody

Supplier:  Active Motif 39807

Catalog No. 50-199-2871

Description

Brg1 (Brahma-related gene 1) is an ATPase subunit of SWI2/SNF2-like chromatin-remodeling complexes that enable access of regulatory and effector proteins in transcription, DNA repair and DNA replication. Although Brg1-containing complexes are not essential for general cell survival, they participate in transcriptional regulation of several hundred genes including those involved in interferon and stress response, immune cells differentiation, neurogenesis, cell cycle etc. and is absolutely necessary for mouse embryogenesis. Brg1 is also involved in cell growth arrest, senescence and tumour supression.

Specifications

• Antigen: SMARCA4 / BRG1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
• Gene Accession No.: P51532, Q3TKT4
• Gene Symbols: Smarca4
• Immunogen: This SMARCA4 / BRG1 antibody was raised against a recombinant protein corresponding to amino acids 214-279 of mouse BRG1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: 3G4
• Conjugate: Unconjugated
• Gene: Smarca4
• Gene Alias: ATP-dependent helicase SMARCA4; b2b508.1Clo; b2b692Clo; BAF190; BAF190A; brahma protein-like 1; Brg1; brg-1; BRG1-associated factor 190A; BRM/SWI2-related gene 1; CSS4; FLJ39786; global transcription activator homologous sequence; homeotic gene regulator; HP1-BP72; hSNF2b; Mitotic growth and transcription activator; MRD16; nuclear protein GRB1; Protein brahma homolog 1; Protein BRG-1; RTPS2; SMARCA4; SNF2; SNF2B; SNF2beta; SNF2-beta; Snf2l4; SNF2LB; SNF2-like 4; sucrose nonfermenting-like 4; SW1/SNF; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4; SWI2; Transcription activator BRG1
• Host Species: Rat
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 20586, 6597
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid