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SMARCB1 Monoclonal Antibody (2C2), Active Motif™
SDP

Catalog No. 501993586
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50-199-3586 100 μg
50-199-3587 10 μg
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Catalog No. 50-199-3586 Supplier Active Motif Supplier No. 61649
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Description

Mouse Monoclonal Antibody

The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2alpha) and Brg-1 (also designated SNF2beta) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits are thought to play regulatory roles. hSNF2L and hSNF2H both appear to be homologs of Drosophila ISWI, a Brm related ATPase that is present in chromatin remodeling complexes other than SWI/SNF, including the NURF (nucleosome remodeling factor).

Specifications

Antigen SMARCB1
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Monoclonal
Clone 2C2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene SMARCB1
Gene Accession No. Q12824
Gene Alias AU020204; BAF47; BOS_16829; BRG1-associated factor 47; CSS3; hSNF5; hSNFS; INI1; Integrase interactor 1 protein; malignant rhabdoid tumor suppressor; MRD15; mSNF5; PPP1R144; protein phosphatase 1, regulatory subunit 144; RDT; RTPS1; Sfh1p; SMARCB1; SNF5; SNF5 homolog; SNF5/INI1; SNF5L1; Snr1; sucrose nonfermenting, yeast, homolog-like 1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; SWI/SNF-related matrix-associated protein; SWI10; SWNTS1; TYE4
Gene Symbols SMARCB1
Host Species Mouse
Immunogen This antibody was raised against full-length recombinant human SMARCB1 protein.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6598
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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