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Invitrogen™ SMARCB1 Polyclonal Antibody
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Catalog No. PIPA553932
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100 μL
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Catalog No. Quantity
PIPA553932 100 μL
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Catalog No. PIPA553932 Supplier Invitrogen™ Supplier No. PA553932
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EKENSPEKFA LKLCSELGLG GEFVTTIAYS IRGQLSWHQK TYAFSENPLP TVEIAIRNTG DADQWCPLLE TLTDAEMEKK IRDQDRNTRR MRRLANTA Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2alpha) and Brg-1 (also designated SNF2beta) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits are thought to play regulatory roles. hSNF2L and hSNF2H both appear to be homologs of Drosophila ISWI, a Brm related ATPase that is present in chromatin remodeling complexes other than SWI/SNF, including the NURF (nucleosome remodeling factor).
TRUSTED_SUSTAINABILITY

Specifications

Antigen SMARCB1
Applications ChIP Assay, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SMARCB1
Gene Accession No. Q12824, Q9Z0H3
Gene Alias AU020204; Baf47; BRG1-associated factor 47; BRG1-associated factor 47 (BAF47); CSS3; hSNF5; hSNFS; INI1; Integrase interactor 1 protein; malignant rhabdoid tumor suppressor; MRD15; mSNF5; PPP1R144; protein phosphatase 1, regulatory subunit 144; RDT; RTPS1; Sfh1p; SMARCB1; smarcb1a; SNF5; SNF5 homolog; SNF5/INI1; SNF5L1; Snr1; Sucrose nonfermenting yeast homolog like 1; sucrose nonfermenting, yeast, homolog-like 1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 isoform a; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1a; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1-A; SWI/SNF-related matrix-associated protein; SWI10; SWNTS1; Transcription factor TYE4; Transcription regulatory protein SNF5; TYE4; Unknown (protein for MGC:138029); zgc:92517
Gene Symbols SMARCB1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SMARCB1. Recombinant protein control fragment (Product #RP-92346).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20587, 361825, 6598
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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