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Invitrogen™ SMARCC2 Polyclonal Antibody
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Catalog No. PIPA519831
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100 μg
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Catalog No. Quantity
PIPA519831 100 μg
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Catalog No. PIPA519831 Supplier Invitrogen™ Supplier No. PA519831
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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with mouse based on sequence homology.

Cdc73 is a tumor suppressor probably involved in transcriptional and post-transcriptional control pathways. Cdc73 is part of the PAF1 complex, a five-subunit protein complex composed of Paf1, Cdc73, Leo1, Rtf1 and Ctr9. PAF1 was first purified from yeast in association with RNA polymerase II and is believed to function in transcription elongation. The yeast PAF (yPAF) complex interacts with RNA polymerase II and coordinates the setting of histone marks associated with active transcription. In addition to coordinating events during transcription (initiation, promoter clearance, and elongation), hPAF also coordinates events in RNA quality control. Cdc73 may also be involved in cell cycle progression through the regulation of cyclin D1/PRAD1 expression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SMARCC2
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA and 0.02% sodium azide; pH 7.4
Gene Smarcc2
Gene Accession No. Q8TAQ2
Gene Alias 5930405J04Rik; BAF170; BRG1-associated factor 170; chromatin remodeling complex BAF170 subunit; CRACC2; DKFZp313D0632; LOC685179; mammalian chromatin remodeling complex BRG1-associated factor 170; Rsc8; similar to SWI/SNF-related matrix-associated actin-dependent regulator of chromatin c2; Smarcc2; SWI/SNF complex 170 kDa subunit; SWI/SNF complex subunit SMARCC2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2; SWI3-like protein
Gene Symbols Smarcc2
Host Species Rabbit
Immunogen Synthetic peptide conjugated to KLH derived from within residues 800 - 900 of Human SMRC2.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6601
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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