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Invitrogen™ SMC2 Polyclonal Antibody
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Catalog No. PIPA5110399
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100 μL
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PIPA5110399 100 μL
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Catalog No. PIPA5110399 Supplier Invitrogen™ Supplier No. PA5110399
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EELAGLKNTA EKYRQLKQQW EMKTEEADLL QTKLQQSSYH KQQEELDALK KTIEESEETL KNTKEIQRKA EEKYEVLENK MKNAEAERER ELKDAQKKLD CAKTKADASS KKMKEKQQEV EAITLELEEL KREHTSYKQQ LEAVNEAIKS YESQIEVMAA EVAKNKESVN KAQEEVTKQK EVITAQDTVI KAKYAEVAKH K.

CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintenance of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behavior of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in humar cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SMC2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.66 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene SMC2
Gene Accession No. O95347, Q8CG48
Gene Alias 5730502P04Rik; AI255214; AW545314; CAP E; CAPE; CAP-E; Chromosome-associated protein E; FGF-inducible protein 16; fibroblast growth factor inducible 16; Fin16; FLJ10093; hCAP-E; PRO0324; SMC protein 2; Smc2; SMC-2; SMC2 (structural maintenance of chromosomes 2, yeast)-like 1; SMC2 protein; SMC2 structural maintenance of chromosomes 2-like 1; Smc2l1; structural maintenance of chromosomes (SMC) family member, chromosome-associated protein E; structural maintenance of chromosomes 2; structural maintenance of chromosomes protein 2; XCAP-E homolog
Gene Symbols SMC2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 700-900 of human SMC2 (NP_006435.2).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10592, 14211
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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