Invitrogen™ SMC2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5115930

Catalog No. PIPA5115930

Description

Antibody detects endogenous levels of total SMC2.

CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintenance of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behavior of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in humar cells.

Specifications

• Antigen: SMC2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SMC2
• Gene Alias: 5730502P04Rik; AI255214; AW545314; CAP E; CAPE; CAP-E; Chromosome-associated protein E; FGF-inducible protein 16; fibroblast growth factor inducible 16; Fin16; FLJ10093; hCAP-E; PRO0324; SMC protein 2; Smc2; SMC-2; SMC2 (structural maintenance of chromosomes 2, yeast)-like 1; SMC2 protein; SMC2 structural maintenance of chromosomes 2-like 1; Smc2l1; structural maintenance of chromosomes (SMC) family member, chromosome-associated protein E; structural maintenance of chromosomes 2; structural maintenance of chromosomes protein 2; XCAP-E homolog
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10592, 14211, 362519
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O95347, Q8CG48
• Gene Symbols: SMC2
• Immunogen: A synthesized peptide derived from human SMC2(Accession O95347), corresponding to amino acid residues K930-G980.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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