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SMC2 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501556818
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50-155-6818 100 μL
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Catalog No. 50-155-6818 Supplier Bethyl Laboratories, Inc Supplier No. A300058A
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintece of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behavior of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in humar cells.

Specifications

Antigen SMC2
Applications Immunocytochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene SMC2
Gene Accession No. O95347
Gene Alias SMC2L1, CAPE, hCAP-E
Gene Symbols SMC2
Host Species Rabbit
Immunogen Between 1150 and C-term
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10592
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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