Invitrogen™ SMC3 Monoclonal Antibody (4C12)

Catalog No.	Quantity
PIMA533001	100 μg

Catalog No. PIMA533001 Supplier Invitrogen™ Supplier No. MA533001

Description

Mouse Monoclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human 293T whole cell, human Hela whole cell, human MCF-7 whole cell, human MDA-MB-453 whole cell, rat thymus tissue, rat liver tissue, mouse thymus tissue, mouse liver tissue. IHC: human lung cancer tissue, human intestinal cancer tissue. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein.

Specifications

• Antigen: SMC3
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 4C12
• Concentration: 500 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 4mg trehalose and 0.05mg sodium azide
• Gene: SMC3
• Gene Accession No.: P97690, Q9CW03, Q9UQE7
• Gene Alias: Bam; Bamacan; basement membrane chondroitin sulfate proteoglycan; basement membrane-associated chondroitin proteoglycan; BMH; CDLS3; chondroitin sulfate proteoglycan 6; chondroitin sulfate proteoglycan 6 (bamacan); chromosome segregation protein SmcD; Chromosome-associated polypeptide; cspg6; HCAP; im:7142991; mad member-interacting protein 1; Mmip1; SMC protein 3; Smc3; SMC-3; SMC3 protein; SMC3L1; SmcD; structural maintenace of chromosomes 3; structural maintenance of chromosomes 3; structural maintenance of chromosomes protein 3; structural maintenance of chromosomes protein 3-like protein; wu:fb22e01; wu:fc30d07
• Gene Symbols: SMC3
• Host Species: Mouse
• Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human SMC3.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 13006, 29486, 9126
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1