Invitrogen™ SMCHD1 Monoclonal Antibody (CL4270)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524709

Catalog No. PIMA524709

Description

Immunogen sequence: DNGRGMTSKQL NNWAVYRLSK FTRQGDFESD HSGYVRPVPV PRSLNSDISY FGVGGKQAVF FVGQSARMIS KPADSQDVHE LVLSKED Highest antigen sequence identity to the following orthologs - mouse 97%, rat 98%.

Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the de novo methyltransferase DNMT3B. Required for DUX4 silencing in somatic cells.

Specifications

• Antigen: SMCHD1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: A6NHR9
• Gene Symbols: SMCHD1
• Immunogen: Recombinant Human SMCHD1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Clone: CL4270
• Conjugate: Unconjugated
• Gene: SMCHD1
• Gene Alias: 4931400A14Rik; AW554188; KIAA0650; mKIAA0650; MommeD1; RGD1307234; SMC hinge domain containing 1; SMC hinge domain-containing protein 1; Smchd1; structural maintenance of chromosomes flexible hinge domain containing 1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 23347
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid