Invitrogen™ SMCHD1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5115932

Catalog No. PIPA5115932

Description

Antibody detects endogenous levels of total SMCHD1.

Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the de novo methyltransferase DNMT3B. Required for DUX4 silencing in somatic cells.

Specifications

• Antigen: SMCHD1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SMCHD1
• Gene Alias: 4931400A14Rik; AW554188; KIAA0650; mKIAA0650; MommeD1; RGD1307234; SMC hinge domain containing 1; SMC hinge domain-containing protein 1; Smchd1; structural maintenance of chromosomes flexible hinge domain containing 1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23347, 316732, 74355
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: A6NHR9, Q6P5D8
• Gene Symbols: SMCHD1
• Immunogen: A synthesized peptide derived from human SMCHD1(Accession A6NHR9), corresponding to amino acid residues V1850-L1900.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG