Invitrogen™ SMCHD1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA558788

Catalog No. PIPA558788

Description

Immunogen sequence: DNGRGMTSKQ LNNWAVYRLS KFTRQGDFES DHSGYVRPVP VPRSLNSDIS YFGVGGKQAV FFVGQSARMI SKPADSQDVH ELVLSKED Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 98%.

Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the de novo methyltransferase DNMT3B. Required for DUX4 silencing in somatic cells.

Specifications

• Antigen: SMCHD1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SMCHD1
• Gene Alias: 4931400A14Rik; AW554188; KIAA0650; mKIAA0650; MommeD1; RGD1307234; SMC hinge domain containing 1; SMC hinge domain-containing protein 1; Smchd1; structural maintenance of chromosomes flexible hinge domain containing 1; structural maintenance of chromosomes flexible hinge domain-containing protein 1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23347
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: A6NHR9
• Gene Symbols: SMCHD1
• Immunogen: Recombinant protein corresponding to Human SMCHD1. Recombinant protein control fragment (Product #RP-98295).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG