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Invitrogen™ SMCR7L Polyclonal Antibody
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Catalog No. PIPA543348
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100 μL
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PIPA543348 100 μL
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Catalog No. PIPA543348 Supplier Invitrogen™ Supplier No. PA543348
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Description

Rabbit Polyclonal Antibody

Peptide sequence: GAAMLGIATL AVKRMYDRAI SAPTSPTRLS HSGKRSWEEP NWMGSPRLLN Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%.

Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP. Does not require ADP for its function in recruiting DNM1L. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen SMCR7L
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene MIEF1
Gene Accession No. Q9NQG6
Gene Alias A230016E22; AI452372; dJ1104E15.3; HSU79252; MID51; Mief1; mitochondrial dynamic protein MID51; mitochondrial dynamic protein of 51 kDa; mitochondrial dynamic protein of 51 kDa homolog; mitochondrial dynamics protein MID51; Mitochondrial dynamics protein of 51 kDa; mitochondrial dynamics protein of 51 kDa homolog; Mitochondrial elongation factor 1; Smcr7l; SMCR7-like protein; smith-Magenis syndrome chromosomal region candidate gene 7 protein-like; Smith-Magenis syndrome chromosome region, candidate 7-like
Gene Symbols MIEF1
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human SMCR7L.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54471
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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