Invitrogen™ SMEK1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA551724

Catalog No. PIPA551724

Description

Immunogen sequence: DGEAVVSPSD KTKNDDDIMD PISKFMERKK LKESEEKEVL LKTNLSGRQS PSFKLSLSSG TKTNLTSQSS TTNLPGSPGS PGSPGSPGSP GSVPKNTSQT AAITTKGGLV GLVDYPDDDE DDDEDEDK Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 97%.

Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.

Specifications

• Antigen: SMEK1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PPP4R3A
• Gene Alias: 1110034C04Rik; BC064465; FLFL1; KIAA2010; mKIAA2010; MSTP033; PP4R3; PP4R3A; Ppp4r3a; protein phosphatase 4 regulatory subunit 3A; protein phosphatase 4, regulatory subunit 3A; RGD1309059; serine/threonine-protein phosphatase 4 regulatory subunit 3A; SMEK homolog 1; SMEK homolog 1, suppressor of mek1; SMEK homolog 1, suppressor of mek1 (Dictyostelium); SMEK1; smk1; smk-1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55671
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6IN85
• Gene Symbols: PPP4R3A
• Immunogen: Recombinant protein corresponding to Human SMEK1. Recombinant protein control fragment (Product #RP-89035).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov