Invitrogen™ SMEK1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597089

Catalog No. PIPA597089

Description

Immunogen sequence: VQTFKGLKLR FEQQRERQDN PKLDSMRSIL RNHRYRRDAR TLEDEEEMWF NTDEDDMEDG EAVVSPSDKT KNDDDIMDPI SKFMERKKLK ESEEKEVLLK TNLSGRQSPS FKLSLSSGTK TNLTSQSSTT NLPGSPGSPG SPGSPGSPGS VPKNTSQTAA ITTKGGLVGL VDYPDDDEDD DEDEDKEDTL PLSKKAKFDS; Positive Samples: HeLa, HepG2, Jurkat, MCF-7, Mouse spleen, Rat brain; Cellular Location: Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center.

Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.

Specifications

• Antigen: SMEK1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PPP4R3A
• Gene Alias: 1110034C04Rik; BC064465; FLFL1; KIAA2010; mKIAA2010; MSTP033; PP4R3; PP4R3A; Ppp4r3a; protein phosphatase 4 regulatory subunit 3A; protein phosphatase 4, regulatory subunit 3A; RGD1309059; serine/threonine-protein phosphatase 4 regulatory subunit 3A; SMEK homolog 1; SMEK homolog 1, suppressor of mek1; SMEK homolog 1, suppressor of mek1 (Dictyostelium); SMEK1; smk1; smk-1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 314388, 55671, 68734
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.71 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q6IN85, Q6P2K6
• Gene Symbols: PPP4R3A
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 395-594 of human SMEK1 (NP_0012712101).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG