Invitrogen™ SMG5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5119884

Catalog No. PIPA5119884

Description

Positive Control: Jurkat cell lysate, Hela cell lysate, 293 cell lysate, THP-1 cell lysate, mouse testis tissue lysates, rat testis tissue lysates, Hela. Subcellular Location: Cytoplasm, Nucleus.

SMG5 plays a role in nonsense-mediated mRNA decay. SMG5 does not have RNase activity by itself. SMG5 promotes dephosphorylation of RENT1. SMG5 is necessary for TERT activity.SMG5 is involved in nonsense-mediated mRNA decay (Ohnishi et al., 2003 [PubMed 14636577]).[supplied by OMIM].

Specifications

• Antigen: SMG5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SMG5
• Gene Alias: BC024683; EST1 telomerase component homolog B; Est1b; EST1-like protein B; Est1p-like protein B; ever shorter telomeres 1B; FLJ34864; hSMG-5; Kiaa1089; LPTS interacting protein; LPTS-interacting protein; LPTSRP1; LPTS-RP1; mKIAA1089; Protein SMG5; RP11-54H19.7; Smg5; SMG-5; SMG-5 homolog; SMG5 homolog nonsense mediated mRNA decay factor; Smg-5 homolog, nonsense mediated mRNA decay factor; Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans); SMG5 nonsense mediated mRNA decay factor; SMG5, nonsense mediated mRNA decay factor
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 229512, 23381, 681012
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Flow Cytometry, Western Blot
• Concentration: 1 mg/mL
• Formulation: TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q6ZPY2, Q9UPR3
• Gene Symbols: SMG5
• Immunogen: Recombinant protein within human SMG5 aa 800-1,000.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov