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Invitrogen™ SMN1 Monoclonal Antibody (5H1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA515858

Catalog No. PIMA515858


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Description

Description

MA5-15858 targets SMN1 in indirect ELISA, IF, IHC, and WB applications and shows reactivity with Human and Non-human primate samples. The MA5-15858 immunogen is purified recombinant fragment of human SMN1 expressed in E. Coli. . MA5-15858 detects SMN1 which has a predicted molecular weight of approximately 39kDa.

The SMN1 gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein - survival motor neuron protein. The SMN complex plays a catalyst role in the assemble of small nuclear ribonucleoproteins, the building blocks of the spliceosome. Mutations in the SMN1 gene are known to cause spinal muscular atrophy 1/2.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

SMN1
Monoclonal
Conc. not determined
Ascites with 0.03% sodium azide
Q16637
SMN1
Purified recombinant fragment of human SMN1 expressed in E. Coli.
RUO
6606
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
5H1
Unconjugated
SMN1
AI849087; BCD541; component of gems 1; Gemin1; Gemin-1; SMA; SMA@; SMA1; SMA2; SMA3; SMA4; Smn; SMN1; SMN2; SMNC; SMNT; survival motor neuron 1; survival motor neuron 1 protein; survival motor neuron protein; survival of motor neuron 1, telomeric; survival of motor neuron protein; T-BCD541; TDRD16A; tudor domain containing 16A
Mouse
100 μL
Primary
Human, Monkey
Antibody
IgG1
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