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Invitrogen™ SMN1 Recombinant Rabbit Monoclonal Antibody (9N9Q6)
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Catalog No. PIMA542936
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100 μL
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PIMA542936 100 μL
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Catalog No. PIMA542936 Supplier Invitrogen™ Supplier No. MA542936
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Description

Rabbit Recombinant Monoclonal Antibody

Positive test controls include: HeLa, HepG2. Immunogen sequence: SEDGCIYPAT IASIDFKRET CVVVYTGYGN REEQNLSDLL SPICEVANNI EQNAQENENE SQVSTDESEN SRSPGNKSDN IKPKSAPWNS FLPPPPPM.

The SMN1 gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein - survival motor neuron protein. The SMN complex plays a catalyst role in the assemble of small nuclear ribonucleoproteins, the building blocks of the spliceosome. Mutations in the SMN1 gene are known to cause spinal muscular atrophy 1/2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SMN1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 9N9Q6
Concentration 1.8 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SMN1
Gene Accession No. O35876, Q16637
Gene Alias AI849087; BCD541; component of gems 1; Gemin1; Gemin-1; SMA; SMA@; SMA1; SMA2; SMA3; SMA4; Smn; SMN1; SMN2; SMNC; SMNT; survival motor neuron 1; survival motor neuron 1 protein; survival motor neuron protein; survival of motor neuron 1, telomeric; survival of motor neuron protein; T-BCD541; TDRD16A; tudor domain containing 16A
Gene Symbols SMN1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 103-200 of human SMN1 (Q16637).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64301, 6606
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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