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Invitrogen™ SMO Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5113312

Catalog No. PIPA5113312


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Description

Description

SMO Polyclonal Antibody for Western Blot, ICC/IF, ELISA

Smoothened drosophila homolog (SMOH) is a serpentine protein belonging to the G-protein coupled receptor Fz/Smo family with 787 aa, seven transmembrane G protein-coupled receptors with 4 glycosylation sites and a putative extracellular amino terminus. Smoothened activated by b-Arrestin 2 and GRK2 acts as a receptor for Shh, the Sonic hedgehog gene product, and is a positive regulator of hedgehog signaling pathway along with the smoothened inhibitor patched protein (PTCH) and regulates vertebrate developmental processes, cellular proliferation and differentiation by activating transcription factor Gli. Smoothened mutants are known to cause sporadic basal cell carcinoma of the skin. It is known to express widely in heart and brain.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

SMO
Polyclonal
Unconjugated
SMO
bent body; bnb; E130215L21Rik; frizzled family member 11; FZD11; Gx; HGNC:11119; Protein Gx; Protein SMOH; seven transmembrane helix receptor; SMO; SMOH; smoothened; Smoothened homolog; smoothened homolog (Drosophila); smoothened, frizzled class receptor; smoothened, frizzled family receptor; smoothened, seven transmembrane spanning receptor
Rabbit
Protein G
RUO
319757, 6608
-20°C or -80°C if preferred
Liquid
ELISA, Western Blot, Immunocytochemistry, Western Blot
2 mg/mL
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
P56726, Q99835
SMO
Recombinant Human Smoothened homolog protein (28-233AA).
100 μg
Primary
Human, Mouse
Antibody
IgG
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