Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA547754

Invitrogen™ SMOC1 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA547754
Change view
Click to view available options
Quantity:
100 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA547754 100 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA547754 Supplier Invitrogen™ Supplier No. PA547754
Add to Cart
Add to Cart

Description

Goat Polyclonal Antibody

In direct ELISAs, approximately 30% cross-reactivity with recombinant human (rh) SMOC-1 is observed and less than 1% cross-reactivity with recombinant mouse SMOC-2 and rhSMOC-2 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Secreted modular calcium-binding protein 1 (SMOC1) is a gene located on chromosome 14q24.2, encoding a member of the SPARC (Secreted Protein, Acidic, and Rich in Cysteine) family of matricellular proteins. SMOC1 is characterized by its multiple domains that facilitate calcium binding and interaction with various components of the extracellular matrix. This protein plays a crucial role in modulating cell-matrix interactions and signaling pathways involved in cellular adhesion, migration, and differentiation. SMOC1 is expressed in multiple tissues, including the eyes, limbs, and the central nervous system, and is essential for developmental processes such as angiogenesis and tissue formation. Mutations in SMOC1 have been linked to ocular conditions like anterior segment dysgenesis and microphthalmia, reflecting its significance in eye development. Current studies focus on the protein's broader implications in developmental disorders and its potential as a therapeutic target in diseases associated with extracellular matrix dysregulation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SMOC1
Applications Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene SMOC1
Gene Accession No. Q8BLY1
Gene Alias 2600002F22Rik; AI848508; OAS; secreted modular calcium binding protein 1; secreted modular calcium-binding protein 1; SMOC1; SMOC-1; SPARC related modular calcium binding 1; SPARC-related gene protein; SPARC-related modular calcium binding protein 1; SPARC-related modular calcium-binding protein 1; SPARC-related protein; Srg
Gene Symbols SMOC1
Host Species Goat
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse SMOC-1 His26-Val452.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 314280, 64075
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.