Invitrogen™ SMPD3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA549140

Catalog No. PA549140

Description

Predicted to react with mouse and rat based on sequence homology.

Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization.

Specifications

• Antigen: SMPD3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SMPD3
• Gene Alias: 4631433G07Rik; AI427456; AW537966; Cca1; confluent 3Y1 cell-associated 1; confluent 3Y1 cell-associated protein 1; fro; neutral sphingomyelin phosphodiesterase 3; neutral sphingomyelinase 2; Neutral sphingomyelinase II; NSMASE2; nSMase-2; SMPD3; Sphingomyelin phosphodiesterase 3; sphingomyelin phosphodiesterase 3, neutral; sphingomyelin phosphodiesterase 3, neutral membrane; sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 55512
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 2 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q9NY59
• Gene Symbols: SMPD3
• Immunogen: KLH conjugated synthetic peptide between 137-165 amino acids from the N-terminal region of human SMPD3.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG