Invitrogen™ SMPD3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA576574

Catalog No. PIPA576574

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization.

Specifications

• Antigen: SMPD3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SMPD3
• Gene Alias: 4631433G07Rik; AI427456; AW537966; Cca1; confluent 3Y1 cell-associated 1; confluent 3Y1 cell-associated protein 1; fro; neutral sphingomyelin phosphodiesterase 3; neutral sphingomyelinase 2; Neutral sphingomyelinase II; NSMASE2; nSMase-2; SMPD3; Sphingomyelin phosphodiesterase 3; sphingomyelin phosphodiesterase 3, neutral; sphingomyelin phosphodiesterase 3, neutral membrane; sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55512, 58994, 94338
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O35049, Q9JJY3, Q9NY59
• Gene Symbols: SMPD3
• Immunogen: Recombinant fusion protein of human SMPD3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov