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Invitrogen™ SMPD4 Polyclonal Antibody
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Catalog No. PIPA561204
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100 μL
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Catalog No. Quantity
PIPA561204 100 μL
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Catalog No. PIPA561204 Supplier Invitrogen™ Supplier No. PA561204
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ASLKADSINK PFAQQCQDLV KVIEDFPAKE LHTIFPWLVE SIFGSLDGVL VGWNLRCLQG RVNPVEYSIV MEFLDPGGPM MKLVYKLQAE DYKFDFPVSY Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 94%.

The protein encoded by SMPD4 is a sphingomyelinase that catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. This gene is activated by DNA damage, cellular stress, and tumor necrosis factor, but it is downregulated by wild-type p53. The encoded protein localizes to the endoplasmic reticulum and Golgi network.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SMPD4
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SMPD4
Gene Accession No. Q9NXE4
Gene Alias 4122402O22Rik; Kiaa1418; mKIAA1418; NET13; neutral membrane (neutral sphingomyelinase-3); neutral sphingomyelinase 3; Neutral sphingomyelinase III; neutral sphingomyelinase-3; NSMASE3; nSMase-3; RGD1310674; SKNY; SKNY protein; Smpd4; Sphingomyelin phosphodiesterase 4; sphingomyelin phosphodiesterase 4, neutral membrane; sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
Gene Symbols SMPD4
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SMPD4. Recombinant protein control fragment (Product #RP-98451).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55627
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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