Invitrogen™ SMPD4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA561966

Catalog No. PIPA561966

Description

Immunogen sequence: LAQLITQAKH TAKSISDQCA ESPAGHSFLS WLGFSSMDTN GSYTANDLDE MGQDSVRKTD EYLEKALEYL RQIFRLSEAQ LRQFTLALGT TQDENGKKQL PDCI Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 84%.

The protein encoded by SMPD4 is a sphingomyelinase that catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. This gene is activated by DNA damage, cellular stress, and tumor necrosis factor, but it is downregulated by wild-type p53. The encoded protein localizes to the endoplasmic reticulum and Golgi network.

Specifications

• Antigen: SMPD4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SMPD4
• Gene Alias: 4122402O22Rik; Kiaa1418; mKIAA1418; NET13; neutral membrane (neutral sphingomyelinase-3); neutral sphingomyelinase 3; Neutral sphingomyelinase III; neutral sphingomyelinase-3; NSMASE3; nSMase-3; RGD1310674; SKNY; SKNY protein; Smpd4; Sphingomyelin phosphodiesterase 4; sphingomyelin phosphodiesterase 4, neutral membrane; sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55627
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9NXE4
• Gene Symbols: SMPD4
• Immunogen: Recombinant protein corresponding to Human SMPD4. Recombinant protein control fragment (Product #RP-98452).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov