SMRT / NCoR2 Monoclonal Antibody (5.1), Active Motif™

Mouse Monoclonal Antibody

Supplier:  Active Motif 61106

Catalog No. 50-199-3146

Description

Steroid and thyroid hormones and retinoic acid regulate a complex array of gene expression activity via intracellular receptor transcription factors belonging to the ligand-dependent nuclear receptor superfamily. Adding to the complexity of function of these transcription factors are associated proteins known as coactivators and corepressors which, as their names suggest, enhance or depress transcription activity of the nuclear receptor with which they associate. Silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) and nuclear receptor corepressor (N-CoR) are related transcriptional corepressors which contain two distinct domains capable of interacting with unliganded nuclear receptors to repress their basal transcriptional activity.

Specifications

• Antigen: SMRT / NCoR2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
• Gene Accession No.: Q9Y618
• Gene Symbols: NCOR2
• Immunogen: This SMRT / NCoR2 antibody was raised against a recombinant protein corresponding to amino acids 2004-2310 of human SMRT / NCoR2.
• Quantity: 10 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: 5.1
• Conjugate: Unconjugated
• Gene: NCOR2
• Gene Alias: CTG repeat protein 26; CTG26; N-CoR; NCOR2; N-CoR2; Nuclear receptor corepressor 2; nuclear receptor co-repressor 2; silencing mediator for retinoid and thyroid hormone receptors; Silencing mediator of retinoic acid and thyroid hormone receptor; silencing mediator of retinoid acid and thyroid hormone receptor; SMAP270; Smrt; SMRTe; SMRTE-tau; T3 receptor-associating factor; Thyroid-, retinoic-acid-receptor-associated corepressor; TNRC14; TRAC; TRAC1; TRAC-1
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 9612
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid