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SMRT / NCoR2 Monoclonal Antibody (5.1), Active Motif™
SDP

Catalog No. 501993146
Encompass
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50-199-3146 10 μg
50-199-3145 100 μg
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Catalog No. 50-199-3146 Supplier Active Motif Supplier No. 61106
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Description

Mouse Monoclonal Antibody

Steroid and thyroid hormones and retinoic acid regulate a complex array of gene expression activity via intracellular receptor transcription factors belonging to the ligand-dependent nuclear receptor superfamily. Adding to the complexity of function of these transcription factors are associated proteins known as coactivators and corepressors which, as their names suggest, enhance or depress transcription activity of the nuclear receptor with which they associate. Silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) and nuclear receptor corepressor (N-CoR) are related transcriptional corepressors which contain two distinct domains capable of interacting with unliganded nuclear receptors to repress their basal transcriptional activity.

Specifications

Antigen SMRT / NCoR2
Applications Western Blot
Classification Monoclonal
Clone 5.1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene NCOR2
Gene Accession No. Q9Y618
Gene Alias CTG repeat protein 26; CTG26; N-CoR; NCOR2; N-CoR2; Nuclear receptor corepressor 2; nuclear receptor co-repressor 2; silencing mediator for retinoid and thyroid hormone receptors; Silencing mediator of retinoic acid and thyroid hormone receptor; silencing mediator of retinoid acid and thyroid hormone receptor; SMAP270; Smrt; SMRTe; SMRTE-tau; T3 receptor-associating factor; Thyroid-, retinoic-acid-receptor-associated corepressor; TNRC14; TRAC; TRAC1; TRAC-1
Gene Symbols NCOR2
Host Species Mouse
Immunogen This SMRT / NCoR2 antibody was raised against a recombinant protein corresponding to amino acids 2004-2310 of human SMRT / NCoR2.
Purification Method Protein G
Quantity 10 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9612
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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