Invitrogen™ SMU1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA554062

Catalog No. PIPA554062

Description

Immunogen sequence: SIEIESSDVI RLIMQYLKEN SLHRALATLQ EETTVSLNTV DSIESFVADI NSGHWDTVLQ AIQSLKLPDK TLIDLYEQVV LELIELRELG AARSLLRQTD PMIML Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

SMU1 (suppressor of Mec8 and Unc-52 homolog), also known as BWD (brain-enriched WD), is a member of the WD-repeat SMU1 family and contains one CTLH domain, one LisH domain and six WD-repeats. SMU1 is a homolog of the C. elegans protein Smu1, a ubiquitously expressed nuclear protein that is believed to play a role in alternative splicing events of Unc-52. In mammals, SMU1 is a component of the spliceosome and appears to exhibit a conserved function, affecting the splicing of the mammalian Unc-52 homolog, namely Perlecan. Mutations in the gene encoding SMU1 may affect the function of the spliceosome.

Specifications

• Antigen: SMU1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Smu1
• Gene Alias: 2600001O03Rik; 2610203K23Rik; AB044414; AI845086; AW556129; Brain-enriched WD repeat-containing protein; brain-enriched WD-repeat protein; BWD; DNA replication regulator and spliceosomal factor; fSAP57; functional spliceosome-associated protein 57; homolog of C. elegans smu-1; SMU1; SMU-1; smu-1 suppressor of mec-8 and unc-52 homolog; smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans); smu-1 suppressor of mec-8 and unc-52 protein homolog; suppressor of Mec and Unc defects 1 homolog; WD40 repeat-containing protein SMU1; WD40 repeat-containing protein SMU1, N-terminally processed
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 117541, 55234, 74255
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.40 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q2TAY7, Q3UKJ7, Q99M63
• Gene Symbols: Smu1
• Immunogen: Recombinant protein corresponding to Human SMU1. Recombinant protein control fragment (Product #RP-92934).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG