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Invitrogen™ SMU1 Polyclonal Antibody
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Catalog No. PIPA554062
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100 μL
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PIPA554062 100 μL
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Catalog No. PIPA554062 Supplier Invitrogen™ Supplier No. PA554062
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SIEIESSDVI RLIMQYLKEN SLHRALATLQ EETTVSLNTV DSIESFVADI NSGHWDTVLQ AIQSLKLPDK TLIDLYEQVV LELIELRELG AARSLLRQTD PMIML Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

SMU1 (suppressor of Mec8 and Unc-52 homolog), also known as BWD (brain-enriched WD), is a member of the WD-repeat SMU1 family and contains one CTLH domain, one LisH domain and six WD-repeats. SMU1 is a homolog of the C. elegans protein Smu1, a ubiquitously expressed nuclear protein that is believed to play a role in alternative splicing events of Unc-52. In mammals, SMU1 is a component of the spliceosome and appears to exhibit a conserved function, affecting the splicing of the mammalian Unc-52 homolog, namely Perlecan. Mutations in the gene encoding SMU1 may affect the function of the spliceosome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SMU1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.40 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Smu1
Gene Accession No. Q2TAY7, Q3UKJ7, Q99M63
Gene Alias 2600001O03Rik; 2610203K23Rik; AB044414; AI845086; AW556129; Brain-enriched WD repeat-containing protein; brain-enriched WD-repeat protein; BWD; DNA replication regulator and spliceosomal factor; fSAP57; functional spliceosome-associated protein 57; homolog of C. elegans smu-1; SMU1; SMU-1; smu-1 suppressor of mec-8 and unc-52 homolog; smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans); smu-1 suppressor of mec-8 and unc-52 protein homolog; suppressor of Mec and Unc defects 1 homolog; WD40 repeat-containing protein SMU1; WD40 repeat-containing protein SMU1, N-terminally processed
Gene Symbols Smu1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SMU1. Recombinant protein control fragment (Product #RP-92934).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 117541, 55234, 74255
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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