Invitrogen™ SNAP alpha Monoclonal Antibody (15D4)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA112453

Catalog No. 01-674-320

Description

SNAP alpha Monoclonal Antibody for Western Blot, IP, ELISA

SNAPs (soluble NSF attachment proteins), acting in concert with SNAREs (SNAP receptors) and the N-ethylmaleimide-sensitive fusion protein (NSF) are required for the fusion of transport vesicles to their target membranes in synaptic transmission, intra-Golgi transport, endosome-to-endosome fusion and transcytotic vesicles-to-plasma membrane transport. Vesicle-to-target membrane docking (initial contact) occurs when the vesicle SNARE binds to its cognate target membrane SNARE. a-SNAP (or b-SNAP in brain) then binds to this docking complex and mediates the binding of NSF and thus the formation of a 20S fusion particle. It is thought that, once NSF is bound, ATP hydrolysis by NSF initiates the fusion process.

Specifications

• Antigen: SNAP alpha
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and no preservative; pH 7.5
• Gene Accession No.: P54920, P54921, P81125
• Gene Symbols: NAPA
• Immunogen: Recombinant human alpha-SNAP.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat, Bovine
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Immunoprecipitation, Western Blot
• Clone: 15D4
• Conjugate: Unconjugated
• Gene: NAPA
• Gene Alias: 1500039N14Rik; alpha snap; alpha soluble NSF attachment protein; alpha-SNAP; Alpha-soluble NSF attachment protein; a-SNAP; AW209189; hydrocephaly with hop gait; hyh; Napa; N-ethylmaleimide sensitive fusion protein attachment protein alpha; N-ethylmaleimide-sensitive factor attachment protein alpha; N-ethylmaleimide-sensitive factor attachment protein, alpha; NSF attachment protein alpha; RA81; Snap; SNAPA; SNAP-alpha; SNARE
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 140673, 518407, 8775
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid