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Invitrogen™ SNAP alpha Polyclonal Antibody
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Catalog No. PIPA521782
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100 μL
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PIPA521782 100 μL
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Catalog No. PIPA521782 Supplier Invitrogen™ Supplier No. PA521782
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HepG2, mouse brain, rat brain. Predicted reactivity: Mouse (97%), Rat (97%), Xenopus laevis (89%), Pig (97%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

SNAPs (soluble NSF attachment proteins), acting in concert with SNAREs (SNAP receptors) and the N-ethylmaleimide-sensitive fusion protein (NSF) are required for the fusion of transport vesicles to their target membranes in synaptic transmission, intra-Golgi transport, endosome-to-endosome fusion and transcytotic vesicles-to-plasma membrane transport. Vesicle-to-target membrane docking (initial contact) occurs when the vesicle SNARE binds to its cognate target membrane SNARE. a-SNAP (or b-SNAP in brain) then binds to this docking complex and mediates the binding of NSF and thus the formation of a 20S fusion particle. It is thought that, once NSF is bound, ATP hydrolysis by NSF initiates the fusion process.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SNAP alpha
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene NAPA
Gene Accession No. P54920, P54921, Q9DB05
Gene Alias 1500039N14Rik; alpha snap; alpha soluble NSF attachment protein; alpha-SNAP; Alpha-soluble NSF attachment protein; a-SNAP; AW209189; hydrocephaly with hop gait; hyh; Napa; N-ethylmaleimide sensitive fusion protein attachment protein alpha; N-ethylmaleimide-sensitive factor attachment protein alpha; N-ethylmaleimide-sensitive factor attachment protein, alpha; NSF attachment protein alpha; RA81; Snap; SNAPA; SNAP-alpha; SNARE
Gene Symbols NAPA
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human alpha SNAP. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 108124, 140673, 8775
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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