Invitrogen™ SNAP25 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587549

Catalog No. PIPA587549

Description

Immunogen sequence: MAEDADMRNE LEEMQRRADQ LADESLESTR RMLQLVEESK DAGIRTLVML DEQGEQLERI EEGMDQINKD MKEAEKNLTD LGKFCGLCVC PCNKLKSSDA YKKAWGNNQD GVVASQPARV VDEREQMAIS GGFIRRVTND ARENEMDENL EQVSGIIGNL RHMALDMGNE IDTQNRQIDR IMEKADSNKT RIDEANQRAT KMLGSG Positive Samples: HeLa, SH-SY5Y, PC-12; Cellular Location: Cell junction, Cell membrane, Cytoplasm, Lipid-anchor, perinuclear region, synapse, synaptosome.

SNAP25 is a t-SNARE involved in the molecular regulation of neurotransmitter release. It may play a role in the synaptic function of specific neuronal systems. SNAP25 associates with proteins involved in vesicle docking and membrane fusion. It also regulates plasma membrane recycling through its interaction with CENPF. Mutations in the gene can results in myasthenic syndrome.

Specifications

• Antigen: SNAP25
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Snap25
• Gene Alias: ALMS1; bA416N4.2; Bdr; blind drunk; CG17676; CG17884; CG40452; CMS18; dJ1068F16.2; Dmel CG40452; Dmel_CG40452; etID17571.20; etID69167.20; fj42b02; fj45g04; fj48c02; FLJ23079; GENA70; HGNC:11132; resistance to inhibitors of cholinesterase 4 homolog; RIC4; RIC-4; SEC9; si:dkeyp-8f4.6; Snap; SNAP 25; snap25; SNAP-25; snap25.1; SNAP-25.1; snap25a; SNAP-25A; SNAP-25B; snp25; sp; SUP; super protein; synaptosomal associated protein-25; synaptosomal-associated 25 kDa protein; Synaptosomal-associated protein 25; synaptosomal-associated protein 25-A; synaptosomal-associated protein, 25 kDa; synaptosomal-associated protein, 25a; synaptosomal-associated protein, 25kDa; synaptosome associated protein 25; synaptosome associated protein 25a; synaptosome associated protein 25kDa; synaptosome-associated protein 25.1; synaptosome-associated protein 25a; wu:fj42b02; wu:fj45g04; wu:fj48c02
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20614, 25012, 6616
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1.99 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: P60879, P60880, P60881
• Gene Symbols: Snap25
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-206 of human SNAP25 (NP_5708241).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov