Invitrogen™ SND1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596455

Catalog No. PIPA596455

Description

Immunogen sequence: MVLSGCAIIV RGQPRGGPPP ERQINLSNIR AGNLARRAAA TQPDAKDTPD EPWAFPAREF LRKKLIGKEV CFTIENKTPQ GREYGMIYLG KDTNGENIAE SLVAEGLATR REGMRANNPE QNRLSECEEQ AKAAKKGMWS EGNGSHTIRD LKYTIENPRH FVDSHHQKPV NAIIEHVRDG SVVRALLLPD YYLVTVMLSG IKCPTFRREA DGSETPEPFA AEAKFFTESR LLQRDVQIIL ESCHNQNILG TILHPNGNIT; Positive Samples: HeLa, Jurkat, HL-60, MCF7, 293T, Mouse liver, Rat liver; Cellular Location: Cytoplasm, Melanosome, Nucleus.

SND1/P100 (staphylococcal nuclease and tudor domain containing 1), also known as TudorSN, functions in the Pim-1 regulation of Myb activity and acts as a transcriptional activator of EBNA-2. It also interacts with EAV, NSP1, GTF2E1 and GTF2E2, and forms a ternary complex with Stat6 and POLR2A. The staphylococcal nuclease-like (SN)-domains directly interact with amino acids 1099-1758 of CBP. SND1/P100 plays an important role in the assembly of Stat6 transcriptome and stimulates IL-4-dependent transcription by mediating interaction between Stat6 and CBP.

Specifications

• Antigen: SND1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Snd1
• Gene Alias: 100 kDa coactivator; 4SNc-Tudor domain protein; 4SNc-Tudor domain protein long form; 4SNc-Tudor domain protein short form; AL033314; EBNA-2 co-activator (100kD); EBNA2 coactivator p100; p100; p100 co-activator; p100 co-activator variant 1; p100 EBNA2 co-activator; p100L; P100-like protein short variant; p100S; similar to Homo sapiens EBNA-2 co-activator (100kDa coactivator); p105 coactivator; SN4TDR; SND p102; SND1; snd1 protein; SND1-BRAF fusion; staphylococcal nuclease and tudor domain containing 1; staphylococcal nuclease domain containing 1; staphylococcal nuclease domain-containing protein 1; TDRD11; testis tissue sperm-binding protein Li 82P; tudor domain-containing protein 11; TudorSN; Tudor-SN; wu:fc27g10
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27044, 56463, 64635
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 0.33 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q66X93, Q78PY7, Q7KZF4
• Gene Symbols: Snd1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 26-285 of human SND1 (NP_0552052).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov