Invitrogen™ SNIP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552676

Catalog No. PIPA552676

Description

Immunogen sequence: NDLEKSVEKI QRDVSHNHRL VPGPELEEKA LVLKQLGETL TELKAHFPGL QSKMRVVLRV EVEAVKFLKE EPQRLDGLLK RCRGVTDTLA QIRR Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 98%.

Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance.

Specifications

• Antigen: SNIP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SRCIN1
• Gene Alias: KIAA1684; mKIAA1684; p130Cas-associated protein; P140; p140Cap; SNAP-25-interacting protein; SNAP25-interacting protein; SNIP; SRC kinase signaling inhibitor 1; SRCIN1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 80725
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9C0H9
• Gene Symbols: SRCIN1
• Immunogen: Recombinant protein corresponding to Human SNIP. Recombinant protein control fragment (Product #RP-90631).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov