Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA570377

Invitrogen™ SnoN Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA570377
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA570377 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA570377 Supplier Invitrogen™ Supplier No. PA570377
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 82%.

TGF-beta is a ubiquitously expressed cytokine that signals through the Smad protein family to regulate numerous cellular processes such as embryonic development and tumorigenesis. This signaling is negatively regulated by Ski, the mammalian homolog of the transforming protein of an avian retrovirus that induces oncogenic transformation of chicken embryo cells, and the related protein SnoN. Like Ski, SnoN functions by binding to the Smad proteins and preventing their phosphorylation, thereby inhibiting their ability to bind DNA and activate the transcription of downstream genes. SnoN is located primarily in the nucleus in cancer tissues or cells, but in the cytoplasm in normal tissues or primary epithelial cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SnoN
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene SKIL
Gene Accession No. Q60665
Gene Alias EGK_11909; LOW QUALITY PROTEIN: ski-like protein; SKI like proto-oncogene; ski/sno related; SKIL; SKI-like; SKI-like oncogene; ski-like protein; ski-like protein-like; SKI-like proto-oncogene; Skir; ski-related oncogene; ski-related oncogene snoN; Ski-related protein; SNO; SnoA; SnoI; SnoN; v-ski sarcoma viral oncogene homolog
Gene Symbols SKIL
Host Species Rabbit
Immunogen synthetic peptide directed towards the middle region of human SnoN (aa 599-648).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20482
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.