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Invitrogen™ SNRNP200 Polyclonal Antibody
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Catalog No. PIPA556114
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PIPA556114 100 μL
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Catalog No. PIPA556114 Supplier Invitrogen™ Supplier No. PA556114
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Rabbit Polyclonal Antibody

Immunogen sequence: LHPRDIDAFW LQRQLSRFYD DAIVSQKKAD EVLEILKTAS DDRECENQLV LLLGFNTFDF IKVLRQHRMM ILYCTLLASA QSEAEKERIM GKMEADPELS KFLY Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 100%.

Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SNRNP200
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SNRNP200
Gene Accession No. O75643
Gene Alias A330064G03Rik; Activating signal cointegrator 1 complex subunit 3-like 1; ASCC3L1; bad response to refrigeration 2 homolog; BC011390; BRR2; BRR2 homolog; HELIC2; Kiaa0788; RP33; small nuclear ribonucleoprotein 200 (U5); small nuclear ribonucleoprotein 200kDa (U5); small nuclear ribonucleoprotein U5 subunit 200; small nuclear ribonucleoprotein, U5 200kDa subunit; SNRNP200; U5 small nuclear ribonucleoprotein 200 kDa helicase; U5 snRNP-specific 200 kDa protein; U5 snRNP-specific protein, 200 kDa (DEXH RNA helicase family); U5-200KD; U5-200-KD
Gene Symbols SNRNP200
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SNRNP200. Recombinant protein control fragment (Product #RP-88770).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23020
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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