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Invitrogen™ SNRNP200 Polyclonal Antibody
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Catalog No. PIPA5110405
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100 μL
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PIPA5110405 100 μL
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Catalog No. PIPA5110405 Supplier Invitrogen™ Supplier No. PA5110405
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: QMVTQAMWSK DSYLKQLPHF TSEHIKRCTD KGVESVFDIM EMEDEERNAL LQLTDSQIAD VARFCNRYPN IELSYEVVDK DSIRSGGPVV VLVQLEREEE VTGPVIAPLF PQKREEGWWV VIGDAKSNSL ISIKRLTLQQ KAKVKLDFVA PATGAHNYTL YFMSDAYMGC DQEYKFSVDV KEAETDSDSD.

Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SNRNP200
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 3.19 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene SNRNP200
Gene Accession No. O75643
Gene Alias A330064G03Rik; Activating signal cointegrator 1 complex subunit 3-like 1; ASCC3L1; bad response to refrigeration 2 homolog; BC011390; BRR2; BRR2 homolog; HELIC2; Kiaa0788; RP33; small nuclear ribonucleoprotein 200 (U5); small nuclear ribonucleoprotein 200kDa (U5); small nuclear ribonucleoprotein U5 subunit 200; small nuclear ribonucleoprotein, U5 200kDa subunit; SNRNP200; U5 small nuclear ribonucleoprotein 200 kDa helicase; U5 snRNP-specific 200 kDa protein; U5 snRNP-specific protein, 200 kDa (DEXH RNA helicase family); U5-200KD; U5-200-KD
Gene Symbols SNRNP200
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1947-2136 of human SNRNP200 (NP_054733.2).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23020
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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