Invitrogen™ SNRPA1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA561053

Catalog No. PIPA561053

Description

Immunogen sequence: VTNKKHYRLY VIYKVPQVRV LDFQKVKLKE RQEAEKMFKG KRGAQLAKDI ARRSKTFNPG AGLPTDKKKG GPSP Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

SNRPA1 (U2 snRNP-A) is located in gene map locus 15q26. 3 and is a 28 kDa protein, isa specific component of U2 snRNP particle and consists of a unique N-terminal leucine-rich region and an extremely hydrophobic RNA-binding C-terminal region. It lacks segments homologous to RNP1 and RNP2, commonA. A motifs found in several RNA-binding proteins. It associates with U2 snRNP and participates in transcription and pre-mRNA splicing. It might play an important role in cell division and proliferation. Patients with connective tissue disorders often produce autoantibodies against snRNP particles.

Specifications

• Antigen: SNRPA1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SNRPA1
• Gene Alias: 1500015N06Rik; Lea1; small nuclear ribonucleoprotein polypeptide A'; Snrpa1; U2 small nuclear ribonucleoprotein A'; U2 small nuclear ribonucleoprotein polypeptide A'; U2 snRNP A'; U2 snRNP-A'
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6627
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P09661
• Gene Symbols: SNRPA1
• Immunogen: Recombinant protein corresponding to Human SNRPA1. Recombinant protein control fragment (Product #RP-99044).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov