Invitrogen™ SNRPA1 Recombinant Rabbit Monoclonal Antibody (2D7M1)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA542616

Catalog No. PIMA542616

Description

Positive test controls include: HepG2, RD, SH-SY5Y, Mouse liver, Mouse brain, Mouse pancreas. The target is usually found in the following locations: Nucleus. Immunogen sequence: QEAEKMFKGK RGAQLAKDIA RRSKTFNPGA GLPTDKKKGG PSPGDVEAIK NAIANASTLA EVERLKGLLQ SGQIPGRERR SGPTDDGEEE MEEDTVTNGS.

SNRPA1 (U2 snRNP-A) is located in gene map locus 15q26. 3 and is a 28 kDa protein, isa specific component of U2 snRNP particle and consists of a unique N-terminal leucine-rich region and an extremely hydrophobic RNA-binding C-terminal region. It lacks segments homologous to RNP1 and RNP2, commonA. A motifs found in several RNA-binding proteins. It associates with U2 snRNP and participates in transcription and pre-mRNA splicing. It might play an important role in cell division and proliferation. Patients with connective tissue disorders often produce autoantibodies against snRNP particles.

Specifications

• Antigen: SNRPA1
• Classification: Recombinant Monoclonal
• Concentration: 0.8 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P09661, P57784
• Gene Symbols: SNRPA1
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 156-255 of human SNRPA1 (P09661).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 2D7M1
• Conjugate: Unconjugated
• Gene: SNRPA1
• Gene Alias: 1500015N06Rik; Lea1; small nuclear ribonucleoprotein polypeptide A'; Snrpa1; U2 small nuclear ribonucleoprotein A'; U2 small nuclear ribonucleoprotein polypeptide A'; U2 snRNP A'; U2 snRNP-A'
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100361269, 6627, 68981
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov