SNRPN Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-6850	Proteintech Group Inc 110701AP150UL	150 μL

Description

The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5′ untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5′ UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure.

Specifications

• Antigen: SNRPN
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: P63162, P63163
• Gene ID (Entrez): 20646, 6638
• Immunogen: SNRPN Fusion Protein Ag1503
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: SNRPN

• Concentration: 0.28 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: HCERN3, PWCR, RT LI, SM D, Sm N, Sm protein D, Sm protein N, SMN, SNRNP N, SNRPN, SNURF SNRPN
• Gene Symbols: SNRPN
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody