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Invitrogen™ SNTB2 Polyclonal Antibody
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Catalog No. PIPA5115945
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PIPA5115945 100 μL
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Catalog No. PIPA5115945 Supplier Invitrogen™ Supplier No. PA5115945
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total SNTB2.

Syntrophins are structurally related proteins located at the neuromuscular synapse and play an important role in dystrophin associated protein (DAP) complex formation. To date there have been three distinct syntrophin isoforms discovered: alpha 1, beta 1, and beta 2. These proteins each contain a PDZ domain, a syntrophin-unique domain (SU), and three pleckstrin homology domains (PH1a,1b and 2). The PDZ domain has been shown to be responsible for binding syntrophin to nNOS and the DAP complex. This association results in localization of the nicotinic acetylcholine receptor to the cytoskeleton via the (S/T)XV C terminus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SNTB2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene SNTB2
Gene Accession No. Q13425, Q61235
Gene Alias 59 kDa dystrophin-associated protein A1 basic component 2; beta-2-syntrophin; D16S2531E; dystrophin-associated protein A1, 59kD, basic component 2; EST25263; Snt2; SNT2B2; SNT3; SNTB2; SNTL; SYN; syntrophin beta 2; syntrophin, basic 2; syntrophin, beta 2; syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2); syntrophin-3; Syntrophin-like
Gene Symbols SNTB2
Host Species Rabbit
Immunogen A synthesized peptide derived from human SNTB2(Accession Q13425), corresponding to amino acid residues Y203-A253.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20650, 6645, 689421
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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