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Invitrogen™ SNURF Polyclonal Antibody
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Catalog No. PIPA566794
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100 μL
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PIPA566794 100 μL
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Catalog No. PIPA566794 Supplier Invitrogen™ Supplier No. PA566794
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LRRTTEQHVPE VEVQVKRRRT ASLSNQECQL YPRRS Highest antigen sequence identity to the following orthologs - mouse 97%, rat 94%.

SNURF is a highly basic protein localized to the nucleus. The evolutionarily constrained open reading frame of its gene is found on a bicistronic transcript which has a downstream ORF encoding the small nuclear ribonucleoprotein polypeptide N. The upstream coding region utilizes the first three exons of the transcript, a region that has been identified as an imprinting center. Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region but the full-length nature of these transcripts has not been determined. An alternate exon has been identified that substitutes for exon 4 and leads to a truncated, monocistronic transcript. Alternative splicing or deletion caused by a translocation event in the 5' UTR or coding region of this gene leads to Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. The function of this protein is not yet known.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SNURF
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SNURF
Gene Accession No. Q9Y675
Gene Alias HCERN3; Sm protein D; Sm protein N; Small nuclear ribonucleoprotein-associated protein N; Sm-D; SMN; Sm-N; snRNP-N; SNRPN; SNRPN upstream reading frame; SNRPN upstream reading frame protein; SNURF; Tissue-specific-splicing protein
Gene Symbols SNURF
Host Species Rabbit
Immunogen Recombinant Human SNURF. Recombinant protein control fragment (Product #RP-107452).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8926
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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