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Invitrogen™ SNX15 Polyclonal Antibody
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Catalog No. PIPA583444
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PIPA583444 100 μL
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Catalog No. PIPA583444 Supplier Invitrogen™ Supplier No. PA583444
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EEDGEGGPTP AYLSQATELI TQALRDEKAG AYAAALQGYR DGVHVLLQGV PSDPLPARQE GVKKKAAEYL KRAEEILRLH LSQLPP Highest antigen sequence indentity to the following orthologs: Mouse - 74%, Rat - 72%.

This gene encodes a member of the sorting nexin family. Members of this family contain a phox domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SNX15
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Snx15
Gene Accession No. Q9NRS6
Gene Alias 1500032B08Rik; clone iota unknown protein; E130013C21Rik; hCG_23393; HSAF001435; OTTHUMP00000035515; SNX15; sorting nexin 15; sorting nexin-15
Gene Symbols Snx15
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SNX15. Recombinant protein control fragment (Product #RP-97287).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29907
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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