Invitrogen™ SNX4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA537062

Catalog No. PIPA537062

Description

This antibody detects endogenous protein at a molecular weight of 60 kDa. Purity is >95% by SDS-PAGE.

SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain. These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases. These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes. The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors.

Specifications

• Antigen: SNX4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SNX4
• Gene Alias: 1810036H14Rik; AI037066; ATG24B; Snx4; sorting nexin 4; sorting nexin-4
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 360725, 69150, 8723
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O95219, Q91YJ2
• Gene Symbols: SNX4
• Immunogen: Synthetic peptide corresponding to amino acids 234-279 of human SNX4.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG