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Invitrogen™ SNX6 Monoclonal Antibody (335CT6.4.6)
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Catalog No. PIMA537538
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400 μL
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Catalog No. Quantity
PIMA537538 400 μL
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Catalog No. PIMA537538 Supplier Invitrogen™ Supplier No. MA537538
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Description

Mouse Monoclonal Antibody

SNX6 Monoclonal Antibody for Western Blot

SNX6 interacts with members of the transforming growth factor-beta family of receptor serine-threonine kinases. These receptors belong to two classes: type II receptors that bind ligand, and type I receptors that are subsequently recruited to transduce the signal. Of the type II receptors, SNX6 was found to interact strongly with ActRIIB and more moderately with wild type and kinase-defective mutants of TbetaRII. Of the type I receptors, SNX6 was found to interact only with inactivated TbetaRI. SNXs 1-4 also interacted with the transforming growth factor-beta receptor family, showing different receptor preferences. Conversely, SNX6 behaved similarly to the other SNX proteins in its interactions with receptor tyrosine kinases. Strong heteromeric interactions were also seen among SNX1, -2, -4, and -6, suggesting the formation in vivo of oligomeric complexes. These findings are the first evidence for the association of the SNX family of molecules with receptor serine-threonine kinases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SNX6
Applications Western Blot
Classification Monoclonal
Clone 335CT6.4.6
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene SNX6
Gene Accession No. Q9UNH7
Gene Alias 2010006G21Rik; 2610032J07Rik; 2810425K19Rik; AU018928; C85963; MSTP010; SNX6; sorting nexin 6; sorting nexin-6; Sorting nexin-6, N-terminally processed; TFAF2; TRAF4-associated factor 2; tumor necrosis factor receptor-associated factor 4(TRAF4)-associated factor 2
Gene Symbols SNX6
Host Species Mouse
Immunogen SNX6 recombinant protein.
Purification Method Protein G
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 58533
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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