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Invitrogen™ SOCS2 Recombinant Rabbit Monoclonal Antibody (6D3F6)
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Catalog No. PIMA535776
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PIMA535776 100 μL
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Catalog No. PIMA535776 Supplier Invitrogen™ Supplier No. MA535776
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: MTLRCLEPSG NGGEGTRSQW GTAGSAEEPS PQAARLAKAL RELGQTGWYW GSMTVNEAKE KLKEAPEGTF LIRDSSHSDY LLTISVKTSA GPTNLRIEYQ DGKFRLDSII CVKSKLKQFD SVVHLIDYYV QMCKDKRTGP EAPRNGTVHL YLTKPLYTSA PSLQHLCRLT INKCTGAIWG LPLPTRLKDY LEEYKFQV.

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon (IFN)-gamma. The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. Knockout studies in mice also suggested a regulatory role of this gene in IGF-1 related growth control.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SOCS2
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 6D3F6
Concentration 2.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SOCS2
Gene Accession No. O14508, O35717, O88582
Gene Alias 8030460M17; AI527257; AW108012; CIS2; CIS-2; Cish2; cytokine inducible SH2-containing protein 2; cytokine-inducible SH2 protein 2; D130043N08Rik; hg; JAB; Socs2; SOCS-2; SSI2; SSI-2; STAT induced STAT inhibitor-2; STATI2; STAT-induced STAT inhibitor 2; STAT-induced STAT inhibitor-2; Suppressor of cytokine signaling 2; suppressor of cytokine signaling-2
Gene Symbols SOCS2
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 216233, 84607, 8835
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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