Invitrogen™ SOCS2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA519813

Catalog No. PIPA519813

Description

This antibody is predicted to react with rat, cow, pig and chimpanzee based on sequence homology.

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon (IFN)-gamma. The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. Knockout studies in mice also suggested a regulatory role of this gene in IGF-1 related growth control.

Specifications

• Antigen: SOCS2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SOCS2
• Gene Alias: 8030460M17; AI527257; AW108012; CIS2; CIS-2; Cish2; cytokine inducible SH2-containing protein 2; cytokine-inducible SH2 protein 2; D130043N08Rik; hg; JAB; Socs2; SOCS-2; SSI2; SSI-2; STAT induced STAT inhibitor-2; STATI2; STAT-induced STAT inhibitor 2; STAT-induced STAT inhibitor-2; Suppressor of cytokine signaling 2; suppressor of cytokine signaling-2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 216233, 8835
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 1% BSA and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O14508, O35717
• Gene Symbols: SOCS2
• Immunogen: Synthetic peptide conjugated to KLH derived from within residues 150 to the C-terminus of Human SOCS2.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG