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Invitrogen™ SOCS7 Polyclonal Antibody
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Catalog No. PIPA519022
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100 μg
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Catalog No. Quantity
PIPA519022 100 μg
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Catalog No. PIPA519022 Supplier Invitrogen™ Supplier No. PA519022
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Description

Goat Polyclonal Antibody

This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

SOCS7 regulates signaling cascades probably through protein ubiquitination and/or sequestration. SOCS7 functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. SOCS7 inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. SOCS7 may be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SOCS7
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene SOCS7
Gene Accession No. O14512
Gene Alias 2310063P06Rik; C85125; Cish7; NAP4; NAP-4; Nck, Ash and phospholipase C binding protein; nck, Ash and phospholipase C gamma-binding protein; NCKAP4; Nck-associated protein 4; SH2 domain containing SOCS box protein SOCS7; SOCS6; SOCS7; SOCS-7; suppressor of cytokine signaling 6; suppressor of cytokine signaling 7
Gene Symbols SOCS7
Host Species Goat
Immunogen Synthetic peptide sequence (DAGRKPKLTRTQS) corresponding to the internal amino acids of SOCS7 (aa 260-273).
Purification Method Ammonium Sulfate Precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 30837
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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