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Invitrogen™ SOD1 Polyclonal Antibody
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Catalog No. PIPA585095
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100 μL
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PIPA585095 100 μL
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Catalog No. PIPA585095 Supplier Invitrogen™ Supplier No. PA585095
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Description

Rabbit Polyclonal Antibody

Antigen Retrieval (IF): citrate buffer, pH 6.0, 15 min, and IHC: EDTA based, pH 8.0 buffer, 15min. Keep as concentrated solution. Predicted reactivity: Mouse (81%), Rat (81%), Pig (80%), Rabbit (82%), Rhesus Monkey (91%), Chimpanzee (100%). Positive Control: 293T, HeLa, NT2D1, SK-N-AS, IMR32, SK-N-SH, U87-MG, mouse brain, Rat brain, F79, F123. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

SOD1 (superoxide dismutase) binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SOD1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.15 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene SOD1
Gene Accession No. P00441, P07632, P08228
Gene Alias ALS; als1; Amyotrophic lateral sclerosis 1 (ALS1); B430204E11Rik; Cu(2+)-Zn2+ superoxide dismutase; Cu/Zn SOD; Cu/Zn superoxide dismutase; Cu/Zn-SOD; CuZn superoxide dismutase; Cu-Zn superoxide dismutase; Cu-Zn superoxide dismutase C-terminal fragment (150AA); CuZnSOD; Cu-Zn-superoxide dismutase; epididymis secretory protein Li 44; HEL-S-44; HGNC:11179; homodimer; hSod1; indophenoloxidase A; Indophenoloxidase A (IPOA); Ipo1; Ipo-1; ipoa; similar to superoxide dismutase; sod; SOD, soluble; sod1; Sod-1; sod1.S; sod1-a; sod1-b; SOD1L1; SODC; superoxide dismutase; superoxide dismutase [Cu-Zn]; Superoxide dismutase [Cu-Zn] A; superoxide dismutase [Cu-Zn] A-like; superoxide dismutase 1; Superoxide Dismutase 1 (SOD1); superoxide dismutase 1 S homeolog; superoxide dismutase 1 soluble; superoxide dismutase 1, soluble; superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)); superoxide dismutase 1, soluble S homeolog; superoxide dismutase, cystolic; XELAEV_18014289mg; XSODA; xsodb
Gene Symbols SOD1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human SOD1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20655, 24786, 6647
Target Species Human, Mouse, Rat, Avian, Reptile
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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