Invitrogen™ SOD1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA585095

Catalog No. PIPA585095

Description

Antigen Retrieval (IF): citrate buffer, pH 6.0, 15 min, and IHC: EDTA based, pH 8.0 buffer, 15min. Keep as concentrated solution. Predicted reactivity: Mouse (81%), Rat (81%), Pig (80%), Rabbit (82%), Rhesus Monkey (91%), Chimpanzee (100%). Positive Control: 293T, HeLa, NT2D1, SK-N-AS, IMR32, SK-N-SH, U87-MG, mouse brain, Rat brain, F79, F123. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

SOD1 (superoxide dismutase) binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

Specifications

• Antigen: SOD1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SOD1
• Gene Alias: ALS; als1; Amyotrophic lateral sclerosis 1 (ALS1); B430204E11Rik; Cu(2+)-Zn2+ superoxide dismutase; Cu/Zn SOD; Cu/Zn superoxide dismutase; Cu/Zn-SOD; CuZn superoxide dismutase; Cu-Zn superoxide dismutase; Cu-Zn superoxide dismutase C-terminal fragment (150AA); CuZnSOD; Cu-Zn-superoxide dismutase; epididymis secretory protein Li 44; HEL-S-44; HGNC:11179; homodimer; hSod1; indophenoloxidase A; Indophenoloxidase A (IPOA); Ipo1; Ipo-1; ipoa; similar to superoxide dismutase; sod; SOD, soluble; sod1; Sod-1; sod1.S; sod1-a; sod1-b; SOD1L1; SODC; superoxide dismutase; superoxide dismutase [Cu-Zn]; Superoxide dismutase [Cu-Zn] A; superoxide dismutase [Cu-Zn] A-like; superoxide dismutase 1; Superoxide Dismutase 1 (SOD1); superoxide dismutase 1 S homeolog; superoxide dismutase 1 soluble; superoxide dismutase 1, soluble; superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)); superoxide dismutase 1, soluble S homeolog; superoxide dismutase, cystolic; XELAEV_18014289mg; XSODA; xsodb
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20655, 24786, 6647
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.15 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P00441, P07632, P08228
• Gene Symbols: SOD1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human SOD1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Avian, Reptile
• Product Type: Antibody
• Isotype: IgG