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Description
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
Specifications
Specifications
| Antigen | SOD2 |
| Applications | Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Monoclonal |
| Clone | 37CT127.5.11.6 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against partial recombinant human SOD2. |
| Dilution | Immunohistochemistry (1:10-1:50) Western Blot (1:2000) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.09% sodium azide) |
| Gene Alias | IPO-B/MNSOD/Mn-SOD |
| Gene Symbols | SOD2 |
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