Invitrogen™ SOD3 Monoclonal Antibody (4GG11G6), PerCP

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA545225

Catalog No. PIMA545225

Description

1 μg/mL of MA5-45225 was sufficient for detection of EC-SOD in 20 μg of human cartilage lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects extracellular SOD approximately 35kDa.

This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.

Specifications

• Antigen: SOD3
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: 2.48mM MES, 95.64mM phosphate with 0.5M EDTA and no preservative; pH 7.4
• Gene Accession No.: O09164, P08294, Q08420
• Gene Symbols: SOD3
• Immunogen: Human extracellular SOD purified from aortas.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Guinea Pig
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: ELISA, Immunohistochemistry, Western Blot, Immunocytochemistry
• Clone: 4GG11G6
• Conjugate: PerCP
• Gene: SOD3
• Gene Alias: AI314465; ALS; ALS1; EC SOD; EC-SOD; ECSODPT; extracellular superoxide dismutase; extracellular superoxide dismutase [Cu-Zn]; MGC20077; SOD 3; SOD3; Sod-3; Superoxide dimutase 3; superoxide dismutase; superoxide dismutase 3; superoxide dismutase 3, extracellular; superoxide dismutase B; testicular tissue protein Li 175
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 100718762, 20657, 25352, 6649
• Content And Storage: 4°C
• Form: Liquid