Invitrogen™ SOD3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA559870

Catalog No. PIPA559870

Description

Immunogen sequence: WTGEDSAEPN SDSAEWIRDM YAKVTEIWQE VMQRRDDDGT LHAACQVQPS ATLDAAQPRV TGVVLFRQLA PRAKLDAFFA LEGFPTEPNS SSRAIHVHQF G Highest antigen sequence identity to the following orthologs: Mouse - 53%, Rat - 50%.

This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.

Specifications

• Antigen: SOD3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SOD3
• Gene Alias: AI314465; ALS; ALS1; EC SOD; EC-SOD; ECSODPT; extracellular superoxide dismutase; extracellular superoxide dismutase [Cu-Zn]; MGC20077; SOD 3; SOD3; Sod-3; Superoxide dimutase 3; superoxide dismutase; superoxide dismutase 3; superoxide dismutase 3, extracellular; superoxide dismutase B; testicular tissue protein Li 175
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6649
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P08294
• Gene Symbols: SOD3
• Immunogen: Recombinant protein corresponding to Human SOD3. Recombinant protein control fragment (Product #RP-102921).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov