Invitrogen™ SOD3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA593329

Catalog No. PIPA593329

Description

Positive Samples: 22Rv1, HL-60, Mouse kidney, Mouse lung; Cellular Location: extracellular space Immunogen sequence: WTGEDSAEPN SDSAEWIRDM YAKVTEIWQE VMQRRDDDGA LHAACQVQPS ATLDAAQPRV TGVVLFRQLA PRAKLDAFFA LEGFPTEPNS SSRAIHVHQF GDLSQGCEST GPHYNPLAVP HPQHPGDFGN FAVRDGSLWR YR.

This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.

Specifications

• Antigen: SOD3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SOD3
• Gene Alias: AI314465; ALS; ALS1; EC SOD; EC-SOD; ECSODPT; extracellular superoxide dismutase; extracellular superoxide dismutase [Cu-Zn]; MGC20077; SOD 3; SOD3; Sod-3; Superoxide dimutase 3; superoxide dismutase; superoxide dismutase 3; superoxide dismutase 3, extracellular; superoxide dismutase B; testicular tissue protein Li 175
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20657, 25352, 6649
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1.52 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O09164, P08294, Q08420
• Gene Symbols: SOD3
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 19-160 of human SOD3 (NP_0030932).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG